Direct reversal of DNA alkylation damage.
نویسندگان
چکیده
3.5.1. Alkylation Chemotherapy 10 3.5.2. Inhibition of hAGT by O6-Benzylguanine 10 3.5.3. Developing More Potent Inhibitors 10 3.6. Application of hAGT in Biotechnology 10 3.6.1. Quantification of AGT 10 3.6.2. Radioactive Imaging of Tumors 11 3.6.3. hAGT Fusion Proteins in Biotechnology 11 4. AlkB Proteins 11 4.1. Oxidative Dealkylation by AlkB 11 4.1.1. E. Coli AlkB 11 4.1.2. Puzzle of AlkB 11 4.1.3. The Unique Repair Function of AlkB 11 4.1.4. Substrates 12 4.1.5. Side Reactions: Uncoupled Turnovers of RKG and Self-Hydroxylation 13
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ورودعنوان ژورنال:
- Chemical reviews
دوره 106 2 شماره
صفحات -
تاریخ انتشار 2006